Moestue, Siver Andreas; Dam, Cornelia Gerarda; Gorad, Saurabh Sayajirao; Kristian, Alexandr; Bofin, Anna M.; Mælandsmo, Gunhild; Engebråten, Olav; Gribbestad, Ingrid S; Bjørkøy, Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Introduction: The phosphatidylinositol 3-kinase (PI3K) pathway is frequently activated in cancer cells through
numerous mutations and epigenetic changes. The recent development of inhibitors targeting different components of
the PI3K pathway may represent a valuable treatment alternative. However, predicting efficacy of these drugs is
challenging, and methods for therapy monitoring are needed. ...